see the picture below.how terrible it is?
Cause
What is this disease?
It is called as LEWANDOWSKY-LUTZ DYSPLASIA Or EPIDERMODYSPLASIA VERRUCIFORMIS
It is related to mutation in EVER1 and EVER2 GENES in chromosome 17.the function of the gene is controlling the release of zinc from cellular stores.we know that zinc is a co factor in the synthesis of viral protein,hence a major role in viral multiplication.because of mutation in EVER1and EVER2 genes,there is no controll in the availability of zinc for viral protein synthesis,unchecked viral growth occurs resulting in LEWANDOWSKY-LUTZ DYSPLASIA
surgery is difficult because of profused blood supply.it can be controlled with antivirals and interferons.anyway hundred percent cure is difficult.ongoing researches are going on this topic.hope more information will be available soon.
Thank you friends
.it is an autosomal recessive condition causing wart like growth in skin.commonly seen in immunocompromised persons because of human papiloma virus .most cases are reported from Indonesia.It is related to mutation in EVER1 and EVER2 GENES in chromosome 17.the function of the gene is controlling the release of zinc from cellular stores.we know that zinc is a co factor in the synthesis of viral protein,hence a major role in viral multiplication.because of mutation in EVER1and EVER2 genes,there is no controll in the availability of zinc for viral protein synthesis,unchecked viral growth occurs resulting in LEWANDOWSKY-LUTZ DYSPLASIA
surgery is difficult because of profused blood supply.it can be controlled with antivirals and interferons.anyway hundred percent cure is difficult.ongoing researches are going on this topic.hope more information will be available soon.
Thank you friends
Cause
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