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Sunday 9 October 2011

TREEMAN DISEASE-HOW IT OCCURS?

see the picture below.how terrible it is?

 






















What is this disease?


 It is called as LEWANDOWSKY-LUTZ DYSPLASIA Or EPIDERMODYSPLASIA VERRUCIFORMIS

It is related to mutation in EVER1 and EVER2 GENES in chromosome 17.the function of the gene is controlling the release of zinc from cellular stores.we know that zinc is a co factor in the synthesis of viral protein,hence a major role in viral multiplication.because of mutation in EVER1and EVER2 genes,there is no controll in the availability of zinc for viral protein synthesis,unchecked viral growth occurs resulting in LEWANDOWSKY-LUTZ DYSPLASIA


surgery is difficult because of profused blood supply.it can be controlled with antivirals and interferons.anyway hundred percent cure is difficult.ongoing researches are going on this topic.hope more information will be available soon.
Thank you friends

Friday 16 September 2011

DIFFERENCE BETWEEN PTT AND APTT

We know ,there are two pathways involved in blood coagulation process ,the intrinsic system and the extrinsic system

Common coagulation pathway is the Intrinsic pathway which is now called as Contact activation pathway


PTT (partial thrombloplastin time) and APTT

Monday 12 September 2011

LIST OF ANTIDOTES



Antidote is an agent which can oppose the action of a substance,that is poisons.









Poison                                                  Agent
Organophosphorous              for cholinergic effect.  Atropine

organocarbomate poison-    Muscarnic effect.  pralidoxime
                                               New agent.      Avizafone

Monday 25 July 2011

Important HEALTH DATES

January 12=Indian youth day
January. 30=antileprosy day
February 12=sexual&reproductive awareness day

Friday 22 July 2011

easy way to make different concentration of DEXTROSE solution using 25 percent DEXTROSE and ISOLYTE P


In pediatrics ,we usually come across conditions where we need different concentration of DEXTROSE solution other than the one which are commonly available in the market such as D 25,D10 , D5etc.we can easily make these solutions very easily using D25(twenty five percent DEXTROSE) and ISOLYTE P

Tuesday 19 July 2011

Why no SUBCUTANEOUS INSULIN in DIABETIC KETO ACIDOSIS

We know DKA is a complication of uncontrolled diabetes mellitus . it may be due to,


1 too little insulin dose
2 skipping doses of insulin
3 conditions causing increased need such as surgery,trauma,pregnancy,stress,puberty,infection etc
4 increased peripheral insulin resistance

Sunday 17 July 2011

CAPSULE ENDOSCOPY

 We know ,how terrifying OGD scopy for the patient nowadays..Think,we can visualize the GI tract by simply swallowing a pill.?Off course,it is possible now.That is called the CAPSULE ENDOSCOPY. 
   



                       CAPSULE ENDOSCOPE is like a pill with a camera,a battery and a transmitter.Then suppose ,where is the light for visualization of GIT.?

Saturday 16 July 2011

LIST OF PHOBIAS

Phobias are irrational fear of an object,situation,or activity.




Here are some of the types of phobia.,

Friday 15 July 2011

GC SCALE in an INTUBATED client with EYE damage

We are using  scale GLAS GOW COMA daily during our clinical practise to assess LOC. Scores of the scale include

Thursday 14 July 2011

Presence of teeth in newborn head fossil

We have studied that tooth development starts in sixth week of intrauterine life,and they remain buried under gum,and appears on sixth month after birth.Now we have got a proof from palentologist about that.They got a newborn skull fossil from kollam,a place in Kerala.

They conducted a CT scan with that skull.To their surprise they found teeth in that fossil mandiable.Now we can firmly believe what we have studied.The presence of precautious dentition in newborn adds to this evidence too.

SERUM CALCIUM LEVELS AND BLOOD PH

We know,normal serum calcium level is 9-11Meq/dl. It is maintained by the combined action of calcitonin and parathormone,hormones from thyroid and parathyroid respectively.




                                    Normal blood pH is

Wednesday 13 July 2011

"pulse" in pulse polio immunization

In India,pulse polio immunization was started on 1995,

mechanism by which salbutamol nebulisation causing Hypokalemia

                            Normally, we are using salbutamol nebulisation in relieving bronchospasm associated with many respiratory disorders such as asthma.Salbutamol is a selective beta2 agonist